3-Hydroxy-2-piperidinone(CAS: 19365-08-3)

3-Hydroxy-2-piperidinone (CAS: 19365-08-3) is a crystalline compound with a molecular weight of approximately 116.15 g/mol. It has a slightly bitter taste and is soluble in water and organic solvents. This compound is moderately reactive, particularly towards nucleophiles and reducing agents.

3-Hydroxy-2-piperidinone is typically synthesized via the Michael addition of acrylonitrile to 2-piperidone, followed by hydrolysis. The reaction is catalyzed by an acid or base, and the process yields the target compound with good selectivity and a high yield.

3-Hydroxy-2-piperidinone (CAS: 19365-08-3) is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in polymer production for its ability to improve the properties of polymer matrices. It also finds applications in the chemical sensor industry for its reactivity.

When handling 3-Hydroxy-2-piperidinone (CAS: 19365-08-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately, and the Safety Data Sheet (SDS) should be consulted for detailed instructions on disposal and emergency procedures.