2-Nitro-3-pyridinol(CAS: 15128-08-2)

2-Nitro-3-pyridinol (CAS: 15128-08-2) is a crystalline solid with a molecular weight of approximately 169.08 g/mol. It has a high solubility in water and organic solvents. Chemically, it is prone to nitro group reduction and can undergo substitution reactions. It is stable under normal conditions but should be stored away from reducing agents and strong bases.

2-Nitro-3-pyridinol is commonly synthesized by the nitration of 3-pyridol with nitric acid in the presence of sulfuric acid as a catalyst. The reaction is carried out in a cold bath to control the nitration process. The yield is typically around 70-80%, and the product can be purified by recrystallization.

2-Nitro-3-pyridinol is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also used in the production of some organic pigments and as a precursor in the development of sensors and semiconductors.

When handling 2-Nitro-3-pyridinol (CAS: 15128-08-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and protective clothing. The substance should be used in a well-ventilated area or with a fume hood. Spills should be handled carefully, and the product should be stored in a cool, dry place away from heat and direct sunlight. Always refer to the Safety Data Sheet (SDS) for detailed information on safe handling and storage.