Dibutyl 2-methylenesuccinate(CAS: 2155-60-4)

Dibutyl 2-methylenesuccinate (CAS: 2155-60-4) is a colorless or slightly yellow liquid. It has a molecular weight of approximately 250.4 g/mol and a boiling point of 251-253°C. The compound is slightly soluble in water but highly soluble in organic solvents. It is known for its reactivity towards nucleophiles and can undergo esterification and ester hydrolysis reactions.

Dibutyl 2-methylenesuccinate (CAS: 2155-60-4) can be synthesized by the esterification of succinic anhydride with n-butanol. The reaction typically involves the use of a Lewis acid catalyst such as aluminum chloride. The process is carried out under mild conditions to achieve high yield and selectivity. The product can be purified by recrystallization or distillation.

Dibutyl 2-methylenesuccinate (CAS: 2155-60-4) is primarily used in the pharmaceutical industry as a precursor for the synthesis of certain bioactive compounds. It is also utilized in the polymer industry as a plasticizer. Additionally, it has applications in the production of sensors and as a chemical intermediate in semiconductor manufacturing due to its reactivity and functional groups.

When handling Dibutyl 2-methylenesuccinate (CAS: 2155-60-4), it is important to use appropriate Personal Protective Equipment (PPE), such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from heat and open flames. Fume hoods should be used when mixing or reacting with the compound. In case of spills, the area should be immediately cleaned up, and the chemical safety data sheet (SDS) should be consulted for specific spill disposal procedures.