N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide(CAS: 51803-78-2)

CAS Number
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Basic Information
Molecular Formula
C13H12N2O5S
Molecular Weight
308.31 g/mol
Physical Properties
Melting Point
148.0 to 152.0 deg-C
Boiling Point
442 oC at 760 mmHg
Density
1.451
Flash Point
221.1oC
Water Solubility
Soluble in water (<50 µg/ml), 1:10 DMSO:PBS (pH 7.2) (<200 µg/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.
Chemical Identifiers
SMILES
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
InChIKey
HYWYRSMBCFDLJT-UHFFFAOYSA-N
Database References
MDL Number
MFCD00079470
Beilstein Registry Number
2421175
FAQ
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide (CAS 51803-78-2) is an organic compound with the molecular formula C15H13N2O5S. It features a sulfonamide group attached to a 4-nitro-2-phenoxyphenyl ring, making it a key intermediate in pharmaceutical and chemical synthesis. The compound is typically a solid at room temperature and exhibits moderate solubility in polar solvents. Its structure is relevant in drug development and research applications involving sulfonamide derivatives.
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide (CAS 51803-78-2) is primarily used in pharmaceutical research as a precursor for drug development, particularly in the synthesis of anti-inflammatory and antimicrobial agents. It also finds applications in organic chemistry for creating complex molecules and in industrial processes requiring sulfonamide-functional compounds. Its utility stems from its reactivity and structural versatility in chemical reactions and compound design.
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide (CAS 51803-78-2) requires careful handling due to potential toxicity. It may cause skin and eye irritation, and inhalation should be avoided. Safety guidelines recommend using personal protective equipment (PPE) such as gloves, goggles, and lab coats. Proper disposal and adherence to OSHA standards are essential to minimize health and environmental risks.
N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide (CAS 51803-78-2) should be stored in a cool, dry place (15-25°C), away from light and moisture. Keep in a sealed, airtight container to maintain stability. Avoid exposure to incompatible substances and ensure storage in a well-ventilated area. Proper labeling and adherence to chemical storage protocols are critical for safety and longevity.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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