3-Fluoro-4-nitrophenol(CAS: 394-41-2)

3-Fluoro-4-nitrophenol (CAS: 394-41-2) is a yellow solid with a crystalline form. Its molecular weight is approximately 184.05 g/mol. It has a high solubility in water and organic solvents. It is moderately reactive, particularly towards nucleophilic substitution and reduction reactions. It is used in the synthesis of other compounds and as a reagent in various chemical processes.

3-Fluoro-4-nitrophenol (CAS: 394-41-2) can be synthesized by the nitration of 3-fluorophenol using nitric acid and sulfuric acid as reagents. The process involves the sequential introduction of nitro groups. Commonly, a mixture of 3-fluorophenol and concentrated nitric acid is heated to achieve the desired product, with careful monitoring of temperature and reaction progress to ensure high selectivity and yield.

3-Fluoro-4-nitrophenol (CAS: 394-41-2) is primarily used in the pharmaceutical industry for the synthesis of intermediates and active pharmaceutical ingredients. It is also utilized in the production of dyes, pigments, and other chemical compounds. Additionally, it plays a role in the development of sensors and materials for electronic applications.

When handling 3-Fluoro-4-nitrophenol (CAS: 394-41-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.