1,3-Bis(benzyloxy)-2-propanol(CAS: 6972-79-8)

1,3-Bis(benzyloxy)-2-propanol is an oily liquid with a molecular weight of approximately 266.26 g/mol. It has a pKa of about 15.3, indicating it is a weak base. The compound is soluble in organic solvents such as ethanol and acetone but less soluble in water. It is moderately reactive towards nucleophiles and can undergo condensation reactions under certain conditions.

1,3-Bis(benzyloxy)-2-propanol can be synthesized by the reaction of 1,3-propanediol with benzyl chloride in the presence of a base like potassium carbonate. The reaction involves etherification, and the product can be purified by column chromatography or recrystallization from organic solvents.

1,3-Bis(benzyloxy)-2-propanol is primarily used in the pharmaceutical and polymer industries. It serves as a starting material for the synthesis of various organic compounds and can be used as a protective group in organic synthesis. Additionally, it has potential applications in the preparation of sensors and semiconductors.

When handling 1,3-Bis(benzyloxy)-2-propanol, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and away from direct sunlight. In case of spillage, it should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for specific handling instructions.