5-Bromo-2-hydroxy-3-methylpyridine(CAS: 89488-30-2)

5-Bromo-2-hydroxy-3-methylpyridine (CAS: 89488-30-2) is a crystalline solid with a molecular weight of approximately 243.04 g/mol. It has a solubility of about 0.5 g/100 mL in water and is relatively stable in air. This compound can undergo substitution reactions and can be used as a precursor in organic synthesis.

5-Bromo-2-hydroxy-3-methylpyridine can be synthesized via bromination of 2-hydroxy-3-methylpyridine using bromine in the presence of a Lewis acid catalyst. The yield is typically around 70-80%, with good selectivity towards the brominated product.

5-Bromo-2-hydroxy-3-methylpyridine is used in the pharmaceutical and chemical industries for the preparation of intermediates and drugs. It also finds applications in the synthesis of sensors and semiconductors as a functional group modification reagent.

When handling 5-Bromo-2-hydroxy-3-methylpyridine, it is important to use appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. Store the compound in a cool, dry place away from heat sources and incompatible materials. In case of spill, handle it with care and refer to the Safety Data Sheet (SDS) for specific instructions.