Tfa-VAL-TYR-VAL-OH(CAS: 64577-63-5)

Tfa-VAL-TYR-VAL-OH (CAS: 64577-63-5) is a crystalline compound with a molecular weight of approximately 500 g/mol. It has a low solubility in water but is soluble in common organic solvents like DMSO and DMF. This compound shows moderate reactivity, particularly in esterifications and amidations. It is stable under normal conditions but should be stored in a cool, dark place to avoid degradation.

Tfa-VAL-TYR-VAL-OH (CAS: 64577-63-5) is synthesized through peptide coupling reactions. Commonly, the synthesis involves the sequential coupling of individual amino acid equivalents (TFA-protected) using HATU or EDC/NHS as coupling reagents. The coupling is typically performed in anhydrous organic solvents like DCM or DMF. The final product is obtained with high selectivity and yield, usually around 80-90%.

Tfa-VAL-TYR-VAL-OH (CAS: 64577-63-5) is primarily used in the pharmaceutical industry for drug development, particularly in peptide synthesis and modification. It is also utilized in the polymer industry for the synthesis of functional polymers and in the semiconductor industry for material characterization due to its unique chemical properties.

When handling Tfa-VAL-TYR-VAL-OH (CAS: 64577-63-5), it is essential to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, use appropriate spill kits and dispose of the material according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.