N-(4-Chlorophenyl)-1,2-benzenediamine(CAS: 68817-71-0)

N-(4-Chlorophenyl)-1,2-benzenediamine is a crystalline solid with a molecular weight of approximately 233.67 g/mol. It has a pKa of about 7.5 and is slightly soluble in water but more soluble in organic solvents like acetone and ethanol. It is relatively stable under normal conditions but can react with strong oxidizing agents.

N-(4-Chlorophenyl)-1,2-benzenediamine is commonly synthesized via amination of 4-chlorobenzenediazonium salt with phenylenediamine. The reaction requires sodium hydroxide as a base and is conducted in an aqueous medium with a yield of about 85%. The process is selective and efficient, making it suitable for large-scale production.

N-(4-Chlorophenyl)-1,2-benzenediamine is used in the pharmaceutical industry for synthesizing certain drugs, in the polymer industry for producing special plastics, and in the semiconductor industry for dopants and sensitizers. It also finds applications in the production of dyes and sensors.

When handling N-(4-Chlorophenyl)-1,2-benzenediamine, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhaling the vapor. Spills should be cleaned up immediately using suitable absorbents. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information and follow all laboratory safety guidelines.