(1S,2S)-1,2-Diphenyl-1,2-ethanediol(CAS: 655-48-1)

(1S,2S)-1,2-Diphenyl-1,2-ethanediol is a colorless crystalline solid with a molecular weight of approximately 254.31 g/mol. It is slightly soluble in water and readily soluble in common organic solvents. Chemically, it is relatively stable but can react with strong acids or bases. Its physical properties include a melting point of 60-62°C and a density around 1.13 g/cm³.

(1S,2S)-1,2-Diphenyl-1,2-ethanediol can be synthesized through a Wittig reaction or a Grignard reaction involving phenyl methyl ketone and sodium ethoxide. The reaction typically proceeds with good yield and selectivity, though the exact conditions may vary depending on the choice of reagents and solvents.

(1S,2S)-1,2-Diphenyl-1,2-ethanediol is primarily used in the pharmaceutical industry as a precursor in the synthesis of various drugs. It also finds applications in the production of polymers, where it serves as a monomer, and in the development of sensors and semiconductors due to its unique molecular structure.

When handling (1S,2S)-1,2-Diphenyl-1,2-ethanediol, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up with care, using appropriate absorbent materials, and waste should be disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.