Fmoc-Thr(Bzl)-OH(CAS: 117872-75-0)

Fmoc-Thr(Bzl)-OH (CAS: 117872-75-0) is a solid with a crystalline form. Its molecular weight is approximately 420.47 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and DMF. Chemically, it is reactive towards nucleophiles and can be used in peptide coupling reactions. It is also amphoteric, meaning it can act as both an acid and a base under certain conditions.

Fmoc-Thr(Bzl)-OH (CAS: 117872-75-0) is typically synthesized through a multi-step process involving the protection of the Thr(Bzl) moiety with Fmoc (fluorenylmethoxycarbonyl) functional group. The synthesis involves the coupling of D-Thr(Bzl)-OH with Fmoc-Cl in the presence of a base like diisopropylethylamine (DIPEA) and a solvent like DMF. The yield and selectivity are high, and the reaction is carefully monitored to ensure optimal conditions.

Fmoc-Thr(Bzl)-OH (CAS: 117872-75-0) is widely used in the pharmaceutical industry for the synthesis of peptides and proteins. It is also utilized in the polymer industry for creating novel biomaterials and in the semiconductor industry for the development of organic electronic devices. Additionally, it has applications in sensor technology and as a building block in organic synthesis.

When handling Fmoc-Thr(Bzl)-OH (CAS: 117872-75-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be used in a fume hood to minimize inhalation risks. Spills should be carefully cleaned up using absorbent materials, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.