1H-Indol-4-amine(CAS: 5192-23-4)

1H-Indol-4-amine (CAS: 5192-23-4) is a crystalline solid with a molecular weight of approximately 129.15 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. Chemically, it is known for its basic nature and ability to form salts with acids. It is stable under normal conditions but reacts with strong acids to form indole derivatives.

1H-Indol-4-amine can be synthesized through various methods, including the reduction of indole-4-carboxylic acid or indole-4-acetic acid using reducing agents like sodium borohydride or lithium aluminum hydride. Another common method involves the deamination of indole-4-acetic acid using catalytic hydrogenation or other chemical means.

1H-Indol-4-amine (CAS: 5192-23-4) is primarily used in the pharmaceutical industry for the synthesis of indole derivatives that have medicinal applications. It also finds use in the polymer industry as a precursor for certain polymeric materials and in the sensor and semiconductor industries for the development of gas sensors and electronic components.

When handling 1H-Indol-4-amine (CAS: 5192-23-4), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. It should be stored in a cool, dry place, away from direct sunlight and heat sources. In the case of a spill, it should be contained and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling guidelines and emergency procedures.