Ethyl 1-benzyl-4-piperidinecarboxylate(CAS: 24228-40-8)

Ethyl 1-benzyl-4-piperidinecarboxylate (CAS: 24228-40-8) is a crystalline solid with a molecular weight of approximately 250.33 g/mol. It is slightly soluble in water and miscible in organic solvents like ethanol and acetonitrile. This compound is known for its low reactivity under normal conditions, but it can react with bases to form salts. It has a pKa of around 3.5, indicating it is a weak acid.

Ethyl 1-benzyl-4-piperidinecarboxylate (CAS: 24228-40-8) is typically synthesized through the reaction of 4-piperidinecarboxylic acid and benzyl alcohol in the presence of an acid catalyst like hydrogen chloride. The product is isolated by recrystallization from ethanol. This method provides a yield of about 80% and the process is selective and efficient.

Ethyl 1-benzyl-4-piperidinecarboxylate (CAS: 24228-40-8) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry as a component in the preparation of certain polymers. Additionally, it is used in the development of sensor materials and as a reagent in the semiconductor industry for specific chemical processes.

Proper handling of Ethyl 1-benzyl-4-piperidinecarboxylate (CAS: 24228-40-8) requires personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat and direct sunlight. In case of a spill, it should be cleaned up immediately using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.