Sodium gentisate(CAS: 4955-90-2)

Sodium gentisate is a white crystalline powder with a molecular weight of approximately 180.15 g/mol. It is slightly soluble in water and ethanol. Chemically, it is relatively stable but can react with strong acids to form gentisic acid. It has a melting point of 238-240°C and is a key intermediate in organic synthesis.

Sodium gentisate can be synthesized by reacting gentisic acid with sodium hydroxide. Common methods include the direct reaction between gentisic acid and sodium hydroxide, with a yield of about 90%, and the use of sodium carbonate as a base. The reaction is typically carried out in an aqueous medium under mild conditions.

Sodium gentisate is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs, including analgesics and antipyretics. It also finds applications in the food industry as a flavor enhancer, and in the cosmetic industry for its antioxidant properties. Additionally, it is used in the polymer industry as a stabilizer.

When handling Sodium gentisate, ensure appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Store the compound in a cool, dry place away from direct sunlight. In case of spill, use appropriate absorbents and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.