1-Chloro-4-vinylbenzene(CAS: 1073-67-2)

1-Chloro-4-vinylbenzene is a yellow liquid with a molecular weight of approximately 150.57 g/mol. It has a melting point of -13°C and a boiling point of 128-130°C. This compound is slightly soluble in water but soluble in most organic solvents. It is reactive and can undergo electrophilic aromatic substitution and addition reactions.

1-Chloro-4-vinylbenzene is typically synthesized via the reaction of chloroform acetone with sodium ethoxide in ethanol. The reaction involves the deprotonation of acetone to form an enolate ion, which then reacts with chloroform to form 1-chloro-4-vinylbenzene. This process is selective and yields a high percentage of the desired product.

1-Chloro-4-vinylbenzene is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the polymer industry for the production of special polymers and in the electronic industry for semiconductor applications and sensor technology.

When handling 1-Chloro-4-vinylbenzene, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be used. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.