6-Methoxy-1-indanone(CAS: 13623-25-1)

6-Methoxy-1-indanone (CAS: 13623-25-1) is a colorless to white crystalline solid with a molecular weight of approximately 174.21 g/mol. It is soluble in common organic solvents such as ethanol and acetone but is poorly soluble in water. Chemically, it is stable under normal conditions but can undergo oxidation. It has a pKa of approximately 4.5.

6-Methoxy-1-indanone can be synthesized through a condensation reaction of 1-indanone with methanol in the presence of a catalytic amount of an acid catalyst, such as sulfuric acid. The reaction yields 6-methoxy-1-indanone with good chemical selectivity and a yield of around 85%. This method is widely used in industrial settings.

6-Methoxy-1-indanone (CAS: 13623-25-1) is used in various industries. It is primarily used in the pharmaceutical sector for intermediates in drug synthesis, as well as in polymer manufacturing for the production of certain resins. It is also utilized in the chemical sensing industry for the development of gas sensors.

When handling 6-Methoxy-1-indanone (CAS: 13623-25-1), proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a well-ventilated area, preferably under a fume hood, to minimize exposure. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.