Methyl 3-nitro-2-thiophenecarboxylate(CAS: 75735-44-3)

Methyl 3-nitro-2-thiophenecarboxylate (CAS: 75735-44-3) is a crystalline solid with a molecular weight of approximately 214.09 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly towards nucleophiles and reducing agents, making it useful in various organic synthesis reactions.

Methyl 3-nitro-2-thiophenecarboxylate (CAS: 75735-44-3) is commonly synthesized via the nitration of methyl 2-thiophenecarboxylate using concentrated nitric acid in the presence of sulfuric acid as a catalyst. The reaction typically provides high yield and good selectivity, making it a reliable method for industrial-scale production.

Methyl 3-nitro-2-thiophenecarboxylate (CAS: 75735-44-3) is primarily used in the pharmaceutical and polymer industries. It serves as an intermediate in the synthesis of various drugs and is also employed in the production of specialty polymers and materials with unique electronic and optical properties.

When handling Methyl 3-nitro-2-thiophenecarboxylate (CAS: 75735-44-3), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and followed by thorough cleaning. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.