3-iodoaniline(CAS: 626-01-7)

3-Iodoaniline (CAS: 626-01-7) is a white to pale yellow crystalline solid with a molecular weight of approximately 216.02 g/mol. It is slightly soluble in water but readily soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly in nucleophilic substitution reactions due to the presence of the iodo group.

3-Iodoaniline (CAS: 626-01-7) is typically synthesized by iodination of aniline using sodium iodide in an aqueous solution. The reaction is usually catalyzed by an acid, such as sulfuric acid, and proceeds via electrophilic aromatic substitution. The yield is generally high, and selectivity is good for this transformation.

3-Iodoaniline (CAS: 626-01-7) is used in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of analgesic and anti-inflammatory drugs. It also finds applications in the production of dyes and pigments. Additionally, it is utilized in the development of certain polymers and as a component in the manufacturing of sensors and semiconductors.

3-Iodoaniline (CAS: 626-01-7) should be handled with caution due to its reactivity and potential for skin and eye irritation. It is recommended to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. In case of a spill, follow the guidelines in the Safety Data Sheet (SDS) for proper cleanup.