Ponatinib(CAS: 943319-70-8)

Ponatinib is a kinase inhibitor with the chemical formula C23H26N4O5. It is a yellow solid with high solubility in dimethyl sulfoxide (DMSO) and is known for its ability to target multiple tyrosine kinases, including BCR-ABL. Ponatinib is used in the treatment of chronic myeloid leukemia (CML) and other cancers.

Ponatinib is primarily used in oncology, particularly for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). It is also being investigated for use in other cancers due to its broad kinase inhibitory activity.

Ponatinib is generally considered safe when used under medical supervision, but it may have side effects such as arterial thrombosis, arrhythmias, and liver toxicity. Proper handling and adherence to safety guidelines are essential to minimize risks during its use and storage.

Ponatinib should be stored in a cool, dry place, away from light, at a temperature between 2°C to 8°C. It is typically kept in a tightly sealed container to prevent moisture exposure and maintain its stability and potency over time.