Amifostine(CAS: 20537-88-6)

Amifostine is a pharmacological radioprotectant, used to protect normal tissues from radiation damage. It has a chemical formula of C12H21NO7S and is a white, crystalline powder. It is also known as Ethyol, an organosulfur compound.

Amifostine is primarily used as a radioprotectant in cancer chemotherapy to protect normal tissues from radiation damage. It is also used in the treatment of radiation-induced cystitis and nephritis. Additionally, it is used in the prevention of iatrogenic kidney damage during cisplatin therapy.

Amifostine is generally considered safe when used as directed. However, it can cause side effects such as nausea, vomiting, and hypotension. It should be handled with care, and healthcare providers should follow safety guidelines and use appropriate personal protective equipment. Toxicity is low, and it is subject to regulatory safety standards.

Amifostine should be stored at 2-8°C (36-46°F) in the dark to maintain its stability. It should be protected from light, kept in a tightly closed container, and stored in a well-ventilated area away from heat and sources of ignition. It should be handled with care to avoid exposure to skin or eyes, and proper disposal methods should be followed.