2-amino-4-phenylbutanoic acid(CAS: 1012-05-1)

2-Amino-4-phenylbutanoic acid is a white to off-white crystalline solid with a molecular weight of approximately 212.26 g/mol. It has a solubility of about 0.2 g/L in water and is slightly soluble in ethanol. It is moderately reactive, capable of undergoing amide and ester formation. It is stable under normal storage conditions but should be protected from moisture and light.

2-Amino-4-phenylbutanoic acid is typically synthesized by the coupling of phenylalanine with an amino acid or via the condensation of 4-phenylbutyric anhydride with an amine. Commonly, the synthesis involves the use of coupling agents like dicyclohexylcarbodiimide (DCC) and 4-(dimethylamino)pyridine (DMAP) as catalysts, with good yield and selectivity.

2-Amino-4-phenylbutanoic acid is used in the pharmaceutical industry for the synthesis of certain drugs due to its biological activity. It is also used in the preparation of organic polymers, particularly in the development of biodegradable materials. Additionally, it can be employed in the manufacturing of sensors and semiconductors.

When handling 2-amino-4-phenylbutanoic acid, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate spill kits, and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for detailed handling procedures and emergency response guidelines.