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7-Amino-4-(trifluoromethyl)-2H-chromen-2-one(CAS: 53518-15-3)

7-Amino-4-(trifluoromethyl)-2H-chromen-2-one
CAS Number

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Basic Information

Molecular Formula
C10H6F3NO2
Molecular Weight
229.16 g/mol

Physical Properties

Melting Point
221-222 °C (lit.)
Boiling Point
314.6°Cat760mmHg
Density
1.4096 (estimate)
Flash Point
144.1°C
Water Solubility
Soluble in dimethyl sulfoxide (25 mg/ml), dimethyl formamide (25 mg/ml), and methanol (25 mg/ml). Insoluble in water.

Chemical Identifiers

SMILES
C1=CC2=C(C=C1N)OC(=O)C=C2C(F)(F)F
InChIKey
JBNOVHJXQSHGRL-UHFFFAOYSA-N

Database References

MDL Number
MFCD00006858
Beilstein Registry Number
4456797

FAQ

The compound 7-Amino-4-(trifluoromethyl)-2H-chromen-2-one (CAS: 53518-15-3) is subject to various regulatory guidelines. Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), it may require specific hazardous labels and safety data sheets. In the European Union, it is regulated under REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) for potential health and environmental impacts. Additionally, the FDA and EPA may have specific requirements for its use in pharmaceuticals and environmental releases, respectively. Compliance with these guidelines is crucial for safe handling and use.
While 7-Amino-4-(trifluoromethyl)-2H-chromen-2-one (CAS: 53518-15-3) is a valuable intermediate in organic synthesis, there are alternatives that can serve similar purposes. For instance, using 4-(trifluoromethyl)-2H-chromen-2-one or related chromenone derivatives can offer comparable functionality. Reagents such as 2,4-difluorobenzaldehyde and 2,4-difluorophenylacetic acid are suitable substitutes in certain syntheses, providing similar structural frameworks and reactivity patterns.
The market and research trends for 7-Amino-4-(trifluoromethyl)-2H-chromen-2-one (CAS: 53518-15-3) are predominantly driven by its applications in pharmaceuticals and agrochemicals. Increasing research efforts are focusing on its use as a precursor in the development of novel drugs and pesticide formulations. Market demand is expected to grow as new chemical entities incorporating this chromenone framework are discovered and developed. Additionally, there is a trend towards exploring its potential in biocatalysis and green chemistry processes.
Proper handling of waste containing 7-Amino-4-(trifluoromethyl)-2H-chromen-2-one (CAS: 53518-15-3) is crucial to ensure environmental and occupational safety. Waste should be collected in appropriate containers and disposed of through incineration or professional waste disposal services. Environmental protection measures include minimizing the release of waste into the environment and ensuring compliance with local and international waste management regulations. Hazardous waste should be labeled and stored in a secure, well-ventilated area until disposal. Compliance with EPA and OSHA guidelines is essential for safe waste management practices.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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