Compound Q&A

Are there alternatives to 7-Amino-4-(trifluoromethyl)-2H-chromen-2-one (CAS: 53518-15-3) in synthesis?

Answer

7-Amino-4-(trifluoromethyl)-2H-chromen-2-one
While 7-Amino-4-(trifluoromethyl)-2H-chromen-2-one (CAS: 53518-15-3) is a valuable intermediate in organic synthesis, there are alternatives that can serve similar purposes. For instance, using 4-(trifluoromethyl)-2H-chromen-2-one or related chromenone derivatives can offer comparable functionality. Reagents such as 2,4-difluorobenzaldehyde and 2,4-difluorophenylacetic acid are suitable substitutes in certain syntheses, providing similar structural frameworks and reactivity patterns.

About

CAS No 53518-15-3
English Name 7-Amino-4-(trifluoromethyl)-2H-chromen-2-one
Molecular Formula C10H6F3NO2
Molecular Weight 229.16 g/mol
SMILES C1=CC2=C(C=C1N)OC(=O)C=C2C(F)(F)F
InChIKey JBNOVHJXQSHGRL-UHFFFAOYSA-N
Last Updated: 2025-10-08 20:02

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