4-Aminobenzaldehyde(CAS: 556-18-3)

4-Aminobenzaldehyde (CAS: 556-18-3) is a white crystalline solid with a molecular weight of 123.12 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. It is an electrophilic aromatic compound and reacts readily with nucleophiles. It has a vapor pressure of less than 0.1 mmHg at 25°C, indicating low volatility. Its solubility makes it useful in various organic synthesis reactions.

4-Aminobenzaldehyde (CAS: 556-18-3) can be synthesized using the reduction of 4-formylbenzeneamine with a suitable reducing agent like sodium borohydride. Another method involves the condensation of salicylaldehyde and hydroxylamine. The yield is typically around 70-80%, and the reaction is performed in aqueous solutions, with careful control of pH and temperature to achieve high selectivity and yield.

4-Aminobenzaldehyde (CAS: 556-18-3) is widely used in the pharmaceutical industry for the synthesis of various drugs. It is also utilized in the production of dyes, pigments, and in the manufacturing of polymers and resins. Additionally, it is used as a starting material in semiconductor and sensor applications due to its unique reactivity and functional groups.

When handling 4-Aminobenzaldehyde (CAS: 556-18-3), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of vapors. Spills should be cleaned up using appropriate absorbents and discarded according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.