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3-[(Dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide(CAS: 783355-60-2)

3-[(Dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide
CAS Number

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Basic Information

Molecular Formula
C21H23N3O5
Molecular Weight
397.43 g/mol

Physical Properties

Density
1.284

Chemical Identifiers

SMILES
CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
InChIKey
MAUCONCHVWBMHK-UHFFFAOYSA-N

Database References

MDL Number
MFCD10565969

FAQ

This compound is a solid with a crystalline form. Its molecular weight is approximately 492.58 g/mol. It has moderate solubility in organic solvents like DMSO and poor solubility in water. The compound is reactive, particularly towards nucleophiles, and shows potential for use in various chemical transformations.
The compound can be synthesized through the condensation of 2-benzofuran-2-carboxylic acid and 4-(hydroxycarbamoyl)phenol, followed by alkylation with dimethylamine. Commonly used solvents include DMF, and the reaction is catalyzed by a suitable base like DIPEA. The yield is typically around 75%. The reaction is selective and efficient under mild conditions.
This compound is used in the pharmaceutical industry for the development of novel drug candidates. It can also be applied in the sensor technology for detection of specific chemicals and in semiconductor manufacturing as a precursor for organic electronics.
When handling this compound, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat should be worn. It should be performed in a fume hood to minimize exposure to volatiles. In case of a spill, it should be carefully cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

Email

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