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Adefovir Dipivoxil(CAS: 142340-99-6)
CAS Number
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Basic Information
Molecular Formula
C20H32N5O8P
Molecular Weight
501.48 g/mol
Physical State
Powder
Physical Properties
Melting Point
99.0 to 103.0 deg-C
Boiling Point
641°C at 760 mmHg
Density
1.35
Flash Point
341.5±34.3 °C
Chemical Identifiers
SMILES
CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C(N=CN=C21)N)OCOC(=O)C(C)(C)C
InChIKey
WOZSCQDILHKSGG-UHFFFAOYSA-N
Database References
MDL Number
MFCD00869897
FAQ
Adefovir Dipivoxil (CAS: 142340-99-6) is a nucleoside analog prodrug used as an antiviral medication. Its chemical formula is C14H22N2O10P, and it appears as a white crystalline powder. It is soluble in water and has a molecular weight of 514.3 g/mol. The compound is designed to improve the bioavailability of adefovir, a potent inhibitor of hepatitis B virus (HBV) replication.
Adefovir Dipivoxil (CAS: 142340-99-6) is primarily used in pharmaceuticals to treat chronic hepatitis B virus (HBV) infection. It works by inhibiting viral DNA polymerase, reducing viral load. Additionally, it is employed in research for studying antiviral mechanisms and may be used in combination therapies. Its applications are limited to medicinal and scientific contexts.
Adefovir Dipivoxil (CAS: 142340-99-6) is generally safe when used as prescribed, but it may cause side effects like renal toxicity and lactic acidosis. Handling precautions include wearing gloves and goggles to avoid skin or eye contact. Safety standards such as ICH and EPA guidelines emphasize proper use and monitoring. Always follow medical advice to ensure safe administration.
Adefovir Dipivoxil (CAS: 142340-99-6) should be stored in a cool, dry place (20-25°C), protected from light. Maintain low humidity levels to prevent degradation. Keep in a sealed, airtight container to ensure stability. Proper storage is critical to preserve efficacy and safety, as per pharmaceutical guidelines.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures