6-Bromo-1H-purine(CAS: 767-69-1)

6-Bromo-1H-purine (CAS: 767-69-1) is a crystalline compound with a molecular weight of approximately 230.02 g/mol. It has a solubility of about 0.2 g/L in water and is slightly soluble in organic solvents. It is moderately reactive, especially towards nucleophilic substitution reactions. The compound is stable under normal conditions but should be stored in a cool, dry place away from moisture and oxidizing agents.

6-Bromo-1H-purine is commonly synthesized through bromination of 1H-purine using bromine in the presence of a base such as sodium hydroxide. The reaction is typically performed in an organic solvent like methanol. The yield is around 70-80%, and the reaction is selective, providing high purity products.

6-Bromo-1H-purine is primarily used in the pharmaceutical industry for the synthesis of purine derivatives with potential therapeutic applications. It is also used in the production of certain dyes and in academic research for studying purine metabolism and related biochemical pathways.

When handling 6-Bromo-1H-purine (CAS: 767-69-1), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work in a well-ventilated area or a fume hood to avoid inhaling bromine vapor. Spills should be handled with caution using appropriate absorbents, and the area should be thoroughly cleaned. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.