(2E)-3-(3-Hydroxy-4-methoxyphenyl)acrylic acid(CAS: 537-73-5)

It is a chemical compound with the formula C14H14O4, characterized by a conjugated double bond and a hydroxy-methoxy substituted phenyl group. This compound is a colorless liquid with a mild aromatic odor, commonly used as an intermediate in pharmaceutical and organic synthesis. Its molecular structure includes a carboxylic acid functional group linked to a para-hydroxy, meta-methoxy phenyl ring, making it valuable in drug development and research.

The compound is primarily used in pharmaceuticals as a building block for drug molecules, in industrial applications for polymer synthesis, and in food science as a flavoring agent. It also serves as a research tool for studying aromatic substitution reactions and biological activity. Its versatility stems from the reactivity of the acrylic acid group and the functional groups on the phenyl ring.

When handled properly, it is considered safe. However, as a chemical intermediate, it requires adherence to safety protocols. Precautions include wearing gloves, goggles, and a lab coat, and ensuring adequate ventilation. Safety data sheets (SDS) recommend avoiding skin and eye contact, while its toxicity is generally low under standard conditions. Always follow OSHA and EPA guidelines for safe use.

Store in a cool, dry place (25°C), away from light and moisture. Use airtight, sealed containers to maintain stability and prevent degradation. Keep in a well-ventilated area to avoid exposure to fumes. It is stable under normal storage conditions but should be protected from heat and humidity to ensure longevity and safety.