N,N'-Bis(1,3-dihydroxy-2-propanyl)-2,4,6-triiodo-5-(lactoylamino)isophthalamide(CAS: 60166-93-0)

N,N'-Bis(1,3-dihydroxy-2-propanyl)-2,4,6-triiodo-5-(lactoylamino)isophthalamide is a crystalline compound with a high molecular weight due to its triiodinated structure. It has poor water solubility but good solubility in organic solvents. The compound is known for its high reactivity, particularly towards nucleophiles, and exhibits significant chemical stability in neutral to slightly acidic conditions. It crystallizes in the monoclinic system and is highly insoluble in water. This compound is also known for its low volatility and good thermal stability.

N,N'-Bis(1,3-dihydroxy-2-propanyl)-2,4,6-triiodo-5-(lactoylamino)isophthalamide is synthesized through a multi-step process involving the iodination of 2,4,6-triiodo-5-carboxylic acid and subsequent amidation with 1,3-dihydroxy-2-propanol and lactoyl chloride. The reaction typically requires the use of a Lewis acid catalyst, such as aluminum chloride, to facilitate the amidation step. The final product is isolated through recrystallization from an appropriate solvent, ensuring a high yield of the desired compound.

N,N'-Bis(1,3-dihydroxy-2-propanyl)-2,4,6-triiodo-5-(lactoylamino)isophthalamide is primarily used in the pharmaceutical industry for its potential therapeutic applications, although specific uses are limited due to its high reactivity. It is also explored in research settings for its unique chemical properties, such as its ability to form stable complexes with metal ions, making it valuable in sensor and semiconductor applications. Further, its triiodinated structure suggests potential uses in materials science for special optical and electronic properties.

When handling N,N'-Bis(1,3-dihydroxy-2-propanyl)-2,4,6-triiodo-5-(lactoylamino)isophthalamide (CAS: 60166-93-0), it is essential to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat. The compound is corrosive and can cause skin and eye irritation. Work should always be conducted in a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials, followed by thorough cleanup and disposal according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.