1-(4-Biphenylyl)-3-(dimethylamino)-2-propen-1-one(CAS: 138716-22-0)

1-(4-Biphenylyl)-3-(dimethylamino)-2-propen-1-one (CAS: 138716-22-0) is a crystalline compound with a molecular weight of 334.39 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. This compound shows moderate reactivity towards nucleophiles and exhibits photochemical properties.

1-(4-Biphenylyl)-3-(dimethylamino)-2-propen-1-one is commonly synthesized via a multistep process involving the reaction of 4-bromophenylboronic acid with dimethylaminopropargyl chloride followed by Suzuki coupling and subsequent ring closure. The process requires mild to moderate conditions and can achieve good yield with appropriate catalysts.

1-(4-Biphenylyl)-3-(dimethylamino)-2-propen-1-one (CAS: 138716-22-0) is used in the pharmaceutical industry for the synthesis of certain drug compounds. It also finds application in the polymer industry, where it can be used as a monomer. Additionally, it is utilized in the production of sensors and as a precursor in semiconductor manufacturing processes.

When handling 1-(4-Biphenylyl)-3-(dimethylamino)-2-propen-1-one (CAS: 138716-22-0), ensure proper ventilation and use a fume hood. Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Avoid skin contact and inhalation. In case of spill, neutralize the compound with an appropriate solvent and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed guidelines.