5-Bromo-3-iodoquinoline(CAS: 1416438-35-1)

5-Bromo-3-iodoquinoline (CAS: 1416438-35-1) is a crystalline solid with a molecular weight of approximately 419.08 g/mol. It is poorly water-soluble, with a solubility of about 0.01 g/L in water. Chemically, it is highly reactive towards nucleophiles due to the electron-withdrawing nature of the bromo and iodo substituents. It is stable under normal conditions but can react with reducing agents.

5-Bromo-3-iodoquinoline (CAS: 1416438-35-1) is typically synthesized via the bromination and subsequent iodination of quinoline. The reaction usually involves the use of N-bromosuccinimide (NBS) and N-iodosuccinimide (NIS) as brominating and iodinating agents, respectively, under appropriate conditions to achieve high yields and selectivity.

5-Bromo-3-iodoquinoline (CAS: 1416438-35-1) is used in various industries, including pharmaceuticals, where it serves as an intermediate in drug synthesis. It is also utilized in the development of sensors for detecting specific chemicals, and in semiconductor materials due to its electronic properties.

When handling 5-Bromo-3-iodoquinoline (CAS: 1416438-35-1), it is essential to use personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated fume hood. Spills should be cleaned up using appropriate absorbent materials, and any waste should be disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.