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N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine(CAS: 231278-20-9)

N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine
CAS Number

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Basic Information

Molecular Formula
C21H14ClFIN3O
Molecular Weight
505.72 g/mol
Physical State
Powder

Physical Properties

Melting Point
223.0 to 227.0 deg-C
Boiling Point
581.3°C at 760 mmHg
Water Solubility
Slightly soluble in water.

Chemical Identifiers

SMILES
C1=CC(=CC(=C1)F)COC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)I)Cl
InChIKey
UHFPFDMMKYQMLC-UHFFFAOYSA-N

Database References

MDL Number
MFCD09998827

FAQ

N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine (CAS: 231278-20-9) is an organic compound with a complex structure featuring a quinazolinamine ring substituted with a 3-chloro-4-[(3-fluorobenzyl)oxy]phenyl group and an iodine atom. It is a white to off-white solid with limited solubility in water but may dissolve in organic solvents. The compound is primarily used in pharmaceutical research and development due to its potential biological activity.
N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine (CAS: 231278-20-9) is mainly used in pharmaceutical research as an intermediate for developing antineoplastic agents and other therapeutic drugs. Its quinazolinamine scaffold is relevant in drug discovery targeting kinase pathways. It may also find applications in chemical synthesis and specialty industries requiring halogenated aromatic compounds.
Safety of N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine (CAS: 231278-20-9) depends on exposure conditions. It is classified as a hazardous chemical due to its halogenated derivatives, requiring protective measures like gloves, goggles, and ventilation. Handling should follow standard chemical safety protocols, and it is not approved for use in food or consumer products. Always consult safety data sheets (SDS) for detailed guidelines.
Store N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-iodo-4-quinazolinamine (CAS: 231278-20-9) in a sealed, airtight container at room temperature (≤25°C) and low humidity (≤60%). Protect from light by keeping it in a dark location. Avoid exposure to moisture and heat to maintain stability. Regularly check for degradation and follow proper chemical storage standards.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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