3-Oxo-5-indanecarbonitrile(CAS: 69975-66-2)

3-Oxo-5-indanecarbonitrile is a white or off-white crystalline solid with a molecular weight of approximately 202.2 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly with nucleophiles, and is susceptible to hydrolysis under basic conditions.

3-Oxo-5-indanecarbonitrile is commonly synthesized through the condensation of indanone with an appropriate nitrile followed by dehydration. This reaction is typically catalyzed by a strong acid, and the process yields the target compound with good selectivity and moderate to high yield, depending on the specific reaction conditions.

3-Oxo-5-indanecarbonitrile (CAS: 69975-66-2) is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer for the production of specific types of plastics, and in the chemical sensor industry for developing gas sensing materials.

When handling 3-Oxo-5-indanecarbonitrile (CAS: 69975-66-2), it is important to use appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be managed carefully, and the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) should be consulted for specific spill and disposal procedures.