Sacubitril(CAS: 149709-62-6)

Sacubitril is a pharmaceutical compound with the CAS number 149709-62-6. It is a neprilysin inhibitor used primarily in the treatment of heart failure. Chemically, it is known as 4-[[3-[[[2-(2-ethoxyethoxy)ethoxy]methoxy]methyl]amino]propyl]benzenesulfonamide. Sacubitril is a white to off-white solid with good solubility in water and is stable under normal storage conditions.

Sacubitril is mainly used in the pharmaceutical industry as a medication for heart failure, particularly in combination with valsartan. It works by inhibiting the enzyme neprilysin, which helps improve cardiac function and reduce symptoms. Additionally, it is used in research for studying the effects of neprilysin inhibition on cardiovascular health and related conditions.

Sacubitril is considered safe when used as directed in medical treatment. It has been approved by regulatory agencies for use in heart failure management. However, like all medications, it should be handled with care, and healthcare professionals should monitor for potential side effects. Proper storage and adherence to safety guidelines are essential to maintain its efficacy and safety profile.

Sacubitril should be stored in a cool, dry place away from direct light. It is typically kept in a sealed container at a temperature between 15°C and 25°C. Maintaining proper humidity levels is important to prevent degradation. Always store the compound in a secure location to avoid contamination and ensure stability over time.