4-Cyano-3-fluorophenyl 4-propylbenzoate(CAS: 86776-51-4)

4-Cyano-3-fluorophenyl 4-propylbenzoate (CAS: 86776-51-4) is a crystalline solid with a molecular weight of approximately 326.34 g/mol. It has a low solubility in water but is soluble in organic solvents such as acetonitrile and dichloromethane. The compound exhibits weak reactivity under normal conditions but can undergo nucleophilic substitution reactions. It is stable in air but should be stored in a desiccator to prevent moisture absorption.

4-Cyano-3-fluorophenyl 4-propylbenzoate is typically synthesized via a condensation reaction between 4-cyanobenzoic acid and 4-tert-butylphenyl alcohol in the presence of a base like triethylamine. The reaction is carried out in an organic solvent such as dichloromethane. The product can be isolated by filtration, recrystallization, and vacuum drying. The yield is around 80%, and the reaction is selective under these conditions.

4-Cyano-3-fluorophenyl 4-propylbenzoate (CAS: 86776-51-4) is primarily used in pharmaceuticals and polymer applications. It serves as a precursor in the synthesis of various drugs and contributes to the modification of polymer properties. Additionally, it is used in the development of sensors for detecting specific chemicals and in the production of certain semiconductors.

When handling 4-Cyano-3-fluorophenyl 4-propylbenzoate (CAS: 86776-51-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The substance should be stored in a cool, dry place, away from direct sunlight and heat sources. Spills should be cleaned up using appropriate absorbents and disposed of in accordance with local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.