amino-PEG8-t-butyl ester(CAS: 756526-06-4)

Amino-PEG8-t-butyl ester (CAS: 756526-06-4) is a water-soluble compound with a molecular weight of approximately 1134. It exists in a crystalline form and has a pKa of around 7.5. It is reactive, particularly towards nucleophiles, which makes it useful for conjugation reactions. Its solubility in water is good, while it is less soluble in organic solvents.

Amino-PEG8-t-butyl ester (CAS: 756526-06-4) is synthesized through the esterification of PEG8-t-butyl ester with an amino-containing compound. Commonly, the reaction involves the use of a catalyst such as 4-dimethylaminopyridine (DMAP) to enhance the reaction rate. The product yields are generally high, with good selectivity towards the desired esterification product.

Amino-PEG8-t-butyl ester (CAS: 756526-06-4) is primarily used in pharmaceuticals for drug delivery systems, in polymers for functionalization, in sensors for detection of specific analytes, and in semiconductors for surface modification. Its ability to modify surfaces and its biocompatibility make it valuable in these applications.

When handling amino-PEG8-t-butyl ester (CAS: 756526-06-4), it is important to wear protective equipment such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. In case of spills, they should be immediately cleaned up with appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for specific handling procedures and emergency response measures.