N-Acetyl-D-phenylalanine(CAS: 10172-89-1)

N-Acetyl-D-phenylalanine is a white crystalline solid with a molecular weight of approximately 221.23 g/mol. It has a pKa of about 8.5 and is slightly soluble in water. The compound is relatively stable, but it can react with strong acids or bases to form other products. It is also susceptible to hydrolysis under alkaline conditions.

N-Acetyl-D-phenylalanine is typically synthesized by acetylation of D-phenylalanine using acetic anhydride in the presence of a catalyst such as an acid. The reaction is usually carried out in a solvent like dichloromethane or acetonitrile. The yield is around 80-85% with good selectivity for the acetylation product.

N-Acetyl-D-phenylalanine is used in various industries, including pharmaceuticals, where it serves as a building block for peptides and proteins. It is also utilized in the production of bioactive compounds, sensors, and as an intermediate in the synthesis of certain polymers. Additionally, it has applications in the food industry as a flavor enhancer.

Handling N-Acetyl-D-phenylalanine requires appropriate personal protective equipment (PPE), including gloves, safety goggles, and lab coat. It should be stored in a cool, dry place away from moisture and strong acids or bases. In the event of a spill, use appropriate spill kits and follow safety data sheet (SDS) guidelines for disposal. Always work in a well-ventilated area or fume hood to minimize inhalation exposure.