VEGF Receptor 2 Kinase Inhibitor I(CAS: 15966-93-5)

CAS Number
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Basic Information
Molecular Formula
C18H18N2O3
Molecular Weight
310.35 g/mol
Chemical Identifiers
SMILES
CCOC(=O)C1=C(NC(=C1C)C=C2C3=CC=CC=C3NC2=O)C
InChIKey
PMUJUSJUVIXDQC-UHFFFAOYSA-N
Database References
MDL Number
MFCD04974538
FAQ
VEGF Receptor 2 Kinase Inhibitor I (CAS: 15966-93-5) is a crystalline compound with a molecular weight of approximately 544.7 g/mol. It has a high solubility in DMSO and moderate solubility in water. This inhibitor is known for its low reactivity under normal conditions but can undergo hydrolysis in the presence of moisture. Its physical properties include a melting point of around 150°C and a density of approximately 1.2 g/cm³.
VEGF Receptor 2 Kinase Inhibitor I (CAS: 15966-93-5) is typically synthesized through multi-step organic synthesis involving the coupling of aryl halides with amines under palladium catalysis. The synthesis requires careful control of reaction conditions, including temperature and solvent selection. The final product is isolated by recrystallization from appropriate solvents, yielding a purified compound with a high degree of selectivity and a yield of about 70%.
VEGF Receptor 2 Kinase Inhibitor I (CAS: 15966-93-5) is primarily used in the pharmaceutical industry for the development of targeted cancer therapies. It is also relevant in the biotech sector for research and development of new kinase inhibitors. Additionally, it can be utilized in academic and industrial laboratories for studying receptor tyrosine kinases and their role in various biological processes.
What precautions should be taken when handling VEGF Receptor 2 Kinase Inhibitor I (CAS: 15966-93-5)?
When handling VEGF Receptor 2 Kinase Inhibitor I (CAS: 15966-93-5), it is crucial to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight and moisture. Always use a fume hood during handling to minimize inhalation risks. In case of a spill, immediately clean up using appropriate materials and consult the Safety Data Sheet (SDS) for detailed instructions.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
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