4-Hydroxy-1-indanone(CAS: 40731-98-4)

4-Hydroxy-1-indanone (CAS: 40731-98-4) is a colorless to light yellow liquid with a molecular weight of approximately 138.16 g/mol. It has a pKa of about 7.4 and is slightly soluble in water. This compound is moderately reactive, especially under basic conditions, and can undergo keto-enol tautomerism. It is soluble in organic solvents such as ethanol and acetone.

4-Hydroxy-1-indanone (CAS: 40731-98-4) can be synthesized from indanone through a hydroxylation reaction using hydrogen peroxide and a suitable catalyst. The reaction is typically conducted in the presence of a strong base like sodium hydroxide. The yield is usually around 70-80%, with high selectivity for the hydroxylation product.

4-Hydroxy-1-indanone (CAS: 40731-98-4) is used in the pharmaceutical industry as a precursor for certain drugs, in sensor technology for detecting organic compounds, and in the polymer industry for the synthesis of special polymers. It is also utilized in semiconductor manufacturing due to its unique chemical properties.

Proper handling of 4-Hydroxy-1-indanone (CAS: 40731-98-4) requires wearing protective equipment such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.