(4S)-4-Hydroxy-L-proline(CAS: 618-27-9)

(4S)-4-Hydroxy-L-proline is a white crystalline solid with a molecular weight of approximately 141.16 g/mol. It is slightly soluble in water and ethanol. The compound is reactive and can undergo hydrolysis under acidic or basic conditions.

(4S)-4-Hydroxy-L-proline can be synthesized via the hydroxylation of L-proline using a hydrogen peroxide/ferrous sulfate system. The reaction yields a 90% pure product with good selectivity and a high yield of 85%.

(4S)-4-Hydroxy-L-proline finds applications in the pharmaceutical industry for the synthesis of prodrugs and as a building block in medicinal chemistry. It is also used in the production of certain polymers and as a component in sensor technologies.

When handling (4S)-4-Hydroxy-L-proline, use personal protective equipment such as gloves and safety goggles. Store in a cool, dry place away from direct sunlight and heat sources. In case of spill, use a fume hood and follow standard lab safety procedures. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.