(1R,4S)-4-Amino-2-cyclopentene-1-carboxylic acid(CAS: 134003-04-6)

(1R,4S)-4-Amino-2-cyclopentene-1-carboxylic acid is a white crystalline solid with a molecular weight of approximately 158.22 g/mol. It has a pKa of 4.7 and is slightly soluble in water. This compound exhibits a moderate reactivity, particularly in amine and carboxylic acid functional group reactions. It is stable under normal storage conditions but reacts with strong bases and acids.

(1R,4S)-4-Amino-2-cyclopentene-1-carboxylic acid can be synthesized via a multi-step process, typically involving the reduction of 2-cyclopentene-1-carboxylic acid with a hydrogenation catalyst, followed by the introduction of an amino group through an aminoalkylation reaction. The yield is around 75-85%, and the reaction conditions must be carefully controlled to achieve high selectivity.

(1R,4S)-4-Amino-2-cyclopentene-1-carboxylic acid is used in the pharmaceutical industry for the synthesis of certain drug molecules. It is also utilized in the polymer industry for the development of functional polymers. Additionally, it has applications in the sensor industry for creating sensitive detection devices and in the semiconductor industry for specific chemical processes.

When handling (1R,4S)-4-Amino-2-cyclopentene-1-carboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using an appropriate absorbent material and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.