2,8-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine(CAS: 1825352-86-0)

2,8-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine is a crystalline compound with a molecular weight of approximately 412.48 g/mol. It has low solubility in water but is soluble in organic solvents like DMSO. The compound is known for its reactivity in organoboron coupling reactions, which makes it useful in synthetic chemistry.

2,8-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine is usually synthesized via a Pd-catalyzed coupling reaction of a boronic acid with a brominated or chlorinated imidazo[1,2-b]pyridazine derivative. The reaction involves the use of a palladium catalyst, a base, and a ligand to achieve high yields and selectivity.

This compound is primarily used in the pharmaceutical and organic synthesis industries due to its reactivity in organoboron coupling reactions. It can also be applied in polymer synthesis and as a building block in the development of new materials.

When handling 2,8-Dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,2-b]pyridazine, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. Store the compound in a dry place and use a fume hood during synthesis. In case of spill, follow the manufacturer's safety data sheet (SDS) for proper disposal and clean-up procedures.