5-Bromo-1,3-benzodioxole(CAS: 2635-13-4)

5-Bromo-1,3-benzodioxole (CAS: 2635-13-4) is a crystalline compound with a molecular weight of approximately 212.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetone. The compound is relatively stable but can react with strong bases and oxidizing agents. This compound is often used as a precursor in organic synthesis and as a reagent in various chemical reactions.

5-Bromo-1,3-benzodioxole can be synthesized via bromination of 1,3-benzodioxole using bromine in the presence of a catalyst such as N-phenyl-N'-(p-toluenesulfonyl)urea (PTSU). The reaction is typically carried out under anhydrous conditions, and the yield can be improved by careful control of the reaction conditions and the use of appropriate solvents. This method provides a high degree of selectivity and good yield.

5-Bromo-1,3-benzodioxole (CAS: 2635-13-4) is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various pharmaceutical compounds and is also used in the production of certain dyes and pigments. Its reactivity in organic chemistry makes it particularly valuable in the development of new materials and sensors.

When handling 5-Bromo-1,3-benzodioxole (CAS: 2635-13-4), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure to the vapor. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be ventilated thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.