N-Benzyl-6-(4-hydroxybenzyl)-8-(1-naphthylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide(CAS: 847591-62-2)

N-Benzyl-6-(4-hydroxybenzyl)-8-(1-naphthylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide is a crystalline compound with a molecular weight of approximately 542.55 g/mol. It has a high solubility in organic solvents like DMSO and moderate solubility in water. The compound is typically stable under normal conditions but may react under acidic or basic conditions. It is not flammable but can undergo hydrolysis and ring-opening reactions.

N-Benzyl-6-(4-hydroxybenzyl)-8-(1-naphthylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide is synthesized through a multi-step process involving coupling reactions, condensation, and derivatization. Commonly, this involves the use of naphthylmethylamine and benzylamine derivatives, followed by condensation with 4-hydroxybenzaldehyde. The synthesis typically yields a high purity product with good selectivity and moderate to high yield.

N-Benzyl-6-(4-hydroxybenzyl)-8-(1-naphthylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide is primarily used in the pharmaceutical industry for its potential as a drug intermediate. It is also explored in the sensor industry for its specific chemical reactivity and can be used in the semiconductor industry for its structural properties.

When handling N-Benzyl-6-(4-hydroxybenzyl)-8-(1-naphthylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure adequate ventilation by working in a fume hood. Spills should be cleaned up with caution using appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS/SDS) for specific handling and disposal instructions.