Macrophage Inhibitory Peptide H-Thr-Lys-Pro-OH(CAS: 41961-56-2)

Macrophage Inhibitory Peptide H-Thr-Lys-Pro-OH is a peptide with a molecular weight of approximately 599.44 Da. It has limited solubility in water and organic solvents. This peptide is relatively stable under normal conditions but may degrade under acidic or basic conditions. It is typically crystalline in form and can be characterized by its specific UV absorption spectrum and mass spectrometry analysis.

Macrophage Inhibitory Peptide H-Thr-Lys-Pro-OH is synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The key steps include coupling of amino acids, cleavage from the resin, and deprotection. Commonly, t-Boc protection is used for threonine and lysine residues, and the final product is obtained with a yield of around 70-80%.

Macrophage Inhibitory Peptide H-Thr-Lys-Pro-OH (CAS: 41961-56-2) is primarily used in the pharmaceutical industry for research purposes, including the development of anti-inflammatory drugs. It is also used in biotechnology for studying immune response and in sensor technology for detecting immune cell activity.

When handling Macrophage Inhibitory Peptide H-Thr-Lys-Pro-OH (CAS: 41961-56-2), it is advised to use personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.