2-Methyl-3-nitropyridine(CAS: 18699-87-1)

2-Methyl-3-nitropyridine is a crystalline compound with a molecular weight of approximately 173.12 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and methanol. Chemically, it is relatively stable but can undergo reduction reactions under certain conditions. The compound is often synthesized using nitration of 2-methylpyridine.

2-Methyl-3-nitropyridine is usually synthesized by the nitration of 2-methylpyridine in the presence of concentrated nitric acid and sulfuric acid as a catalyst. The reaction is carried out at low temperatures to achieve high selectivity and yield. The product is then purified by crystallization or distillation.

2-Methyl-3-nitropyridine is used in various industries including pharmaceuticals for the synthesis of certain drugs, and in the production of organic pigments and dyes. It is also used in the development of sensors and as a precursor in the semiconductor industry.

When handling 2-Methyl-3-nitropyridine, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, immediately clean up using appropriate absorbent materials and follow the safety data sheet (SDS) for further guidance. Storage should be in a cool, dry place away from sources of ignition and incompatible materials.