8-Chloro-3-quinolinol(CAS: 25369-39-5)

8-Chloro-3-quinolinol is a crystalline compound with a molecular weight of approximately 212.62 g/mol. It has a solubility of about 0.15 g/L in water at 25°C. Chemically, it is relatively stable but can react with strong bases and acids. The compound is known for its ability to form complexes and is used in various applications due to its reactivity.

8-Chloro-3-quinolinol is typically synthesized by the reaction of 3-quinolinol with thionyl chloride followed by purification steps. This process involves the substitution of the hydroxyl group with a chlorine atom, yielding the desired product with good selectivity and moderate to high yield.

8-Chloro-3-quinolinol finds applications in the pharmaceutical industry for the synthesis of certain drugs, as well as in the sensor industry for its use in detecting specific chemicals. It is also used in the synthesis of pigments and other organic compounds.

When handling 8-Chloro-3-quinolinol, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled with care, and proper safety data sheets (SDS) should be consulted for detailed emergency procedures.