Dibenzo[b,d]furan-3-ylboronic acid(CAS: 395087-89-5)

Dibenzo[b,d]furan-3-ylboronic acid is a solid with a crystalline form. It has a molecular weight of approximately 264.3 g/mol and a melting point of around 250°C. This compound is slightly soluble in common organic solvents like DMSO and ethanol. Chemically, it is reactive towards nucleophiles, making it useful in various synthetic transformations.

Dibenzo[b,d]furan-3-ylboronic acid can be synthesized via a multistep process involving the preparation of dibenzo[b,d]furan and subsequent protection with a boronic acid derivative. Commonly, this involves a combination of Suzuki coupling reactions and esterification steps, often using catalysis with palladium and base conditions. The reaction typically yields a high purity product with good selectivity and yield.

Dibenzo[b,d]furan-3-ylboronic acid finds applications in various industries, particularly in pharmaceuticals and materials science. It is used as a key intermediate in the synthesis of drug candidates and in the development of advanced materials such as polymers and sensors. Additionally, it plays a role in the production of semiconductors due to its unique electronic properties.

When handling dibenzo[b,d]furan-3-ylboronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted under a fume hood due to its reactivity. Spills should be handled carefully, using appropriate absorbents, and the area should be ventilated to prevent inhalation. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.