(R)-2-Amino-2-methylpent-4-enoic acid(CAS: 96886-56-5)

(R)-2-Amino-2-methylpent-4-enoic acid is a white crystalline solid with a molecular weight of approximately 141.17 g/mol. It has a pKa of about 2.5. The compound has a moderate solubility in water and is soluble in common organic solvents. It is prone to hydrolysis and can undergo addition reactions with nucleophiles. This property makes it reactive in various chemical processes.

(R)-2-Amino-2-methylpent-4-enoic acid is usually synthesized through the alkylation of a known precursor followed by amination. Common methods include the use of sodium hydride and methylmagnesium bromide as reagents, with high selectivity and moderate to good yields. The exact synthetic route can vary based on the availability of starting materials and desired purity.

(R)-2-Amino-2-methylpent-4-enoic acid finds applications in pharmaceuticals, where it serves as an intermediate for drug synthesis. It is also used in the development of polymers and sensors due to its reactivity and functional groups. In the semiconductor industry, it may be used in the fabrication of electronic materials, although specific applications are limited.

When handling (R)-2-Amino-2-methylpent-4-enoic acid, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation. Avoid contact with skin and eyes. Store in a cool, dry place away from heat and ignition sources. In case of spill, neutralize with an appropriate absorbent and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed information.