5-Bromouridine(CAS: 957-75-5)

5-Bromouridine (CAS: 957-75-5) is a crystalline solid with a molecular weight of approximately 243.03 g/mol. It has a solubility of about 0.5 mg/mL in water and is relatively stable under neutral conditions. Chemically, it reacts with nucleophilic reagents to form new bonds. It is commonly used in biochemical research and drug development.

5-Bromouridine is typically synthesized by bromination of uridine. The reaction is carried out using bromine in the presence of a suitable solvent under anhydrous conditions. The yield can be as high as 80% with high selectivity for the bromination site.

5-Bromouridine (CAS: 957-75-5) is utilized in various industries, including pharmaceuticals for drug development, polymers for material science, and sensors for bioanalysis. It is also used in semiconductors for certain applications requiring precise molecular modification.

When handling 5-Bromouridine (CAS: 957-75-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from direct sunlight. If a spill occurs, it should be handled in a fume hood using proper clean-up techniques. Always refer to the safety data sheet (SDS) for detailed safety information.